Prefrontalcortex相关论文
目的:探讨前额叶皮质区小胶质细胞活化对卒中后抑郁小鼠远期空间记忆功能的影响。方法:取48只C57BL/6雄性小鼠按照随机数字表法分......
目的:评价内侧前额叶皮质(mPFC)小胶质细胞P2Xn 7受体在大鼠神经病理性痛中的作用及其与自噬的关系。n 方法:SPF级健康成......
During free exploration,the emergence of patterned and sequential behavioral responses to an unknown environment reflect......
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Grey matter volume abnormalities in patients with bipolar I depressive disorder and unipolar depress
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In this study, one-trial step-through task has been applied to reveal the effect of prefrontal infralimbic cortex GABAA ......
The “left behind children” phenomenon is a serious social issue in China,depriving the relationship between parents an......
Behavior deficits and region specific alterations in local field potential oscillations in APP/PS1 m
Alzheimers disease(AD)is the leading cause of dementia,estimated to affect more than 30 million individuals worldwide....
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CONTENTS OF DOPAMINE AND ITS METABOLITIES IN NAC AND PFC OF SCHIZOPHRENIC RATS BY ELECTRIC STIMULATI
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Activation of cystic fibrosis transmembrane conductance regulator modulates excitability of rat pref
Objective Cystic fibrosis transmembrane conductance regulator(CFTR),an ATP-binding chloride channel,is regulated by intr......
Oscillatory firing is an important process in neural system for presenting, integrating and synchronizing neuronal signa......
Embryonic NMDAR blockade induces anxiety-like behavior by interrupting NMDAR development in both hip
Postnatal NMDA receptor(NMDAR)blockade causes neuronal deficient in adolescence and adult life....
Effects of acute and chronic stress on spatial learning-memory function and expression of c-fos in t
Objective To investigate the effects of acute and chronic stress on the spatial learning-memory function in mice and its......
Stress during a Critical Postnatal Period Induces Region-Specific Structural Abnormalities and Dysfu
Objective During the early postnatal period,environmental influences play a pivotal role in shaping the development of t......
The effects of short-term sleep deprivation on the neuronal functions in the spatial learning and me
Sleep is known as a brain state that increases the clearance of neurotoxic waste products and promotes learning-related ......
Mammalian infants face a significant challenge in early life.Parent-infant relationships can initiate long-term developm......
Curcumin Inhibits Glutamate Release in Nerve Terminals from Rat Prefrontal Cortex: Possible Relevanc
There is abundant evidence suggesting the relevance of glutamate to depression and antidepressant mechanisms.Curcumin, a......
Inhibition of calcineurin in the prefrontal cortex induced depressive-like behavior through mTOR sig
Rational Although it has been recognized that inhibition of calcineurin induced depressive-like behavior, the underlying......
Effects of NR2A overexpression on prefrontal synaptic plasticity and prefrontal cortex-related memor
Objective N-methyl-D-aspartate receptors (NMDARs) play an important role in learning and memory.NR2A and NR2B subunits a......
RNA interference-mediated phosphodiesterase-4D knockdown in the prefrontal cortex elicits antidepres
OBJECTIVE Phosphodiesterase 4 (PDE4), specific for cyclic AMP (cAMP)-hydrolyzing, has four isoforms (PDE4A-D) with at le......
THE INFLUENCE OF ADOLESCENT COCAINE EXPOSURE ON PSYCHIATRIC BEHAVIORS IN ADULT ANIMALS: A PRELIMINAR
In humans,substances use during adolescence increases the risk of psychiatric disorders and drug addiction in adulthood.......
Alterations of prefrontal cortical microRNAs in methamphetamine self-administering rats:from control
OBJECTIVE Drug addiction is a process that transits from recreative and regular drug use into compulsive drug use.The tw......
Stress is the response to the stimulus of environment.Cognitive function is the ability to learn,retain,recall informati......
Decoding value-related signal represented in multiple areas of the prefrontal cortex using ECoG elec
Decision making is one of the important mental processes.For making a decision between multiple options,the values of th......
Despite high prevalence of anxiety accompanying with chronic pain, the mechanisms underlying pain-related anxiety are la......
Effects of estrogen treatment on behavior and expression of BDNF and p TrkB in prefrontal cortex and
To determine the effect of estrogen(E2) on behavior changes of depression, and expression profiles of brain-derived neur......
N-acetylaspartylglutamate (NAAG) peptidase inhibitor 2-PMPA elevates extracellular NAAG levels and i
Phencyclidine (PCP), an open channel antagonist of the NMDA subtype of glutamate receptor, induces schizophrenia-like be......
Objective Inhibition of phosphodiesterase-4 (PDE4) increases phosphorylation of the cAMP response element binding protei......
Neuronal microcircuitry represents the communications between various individual neurons,mainly consisting of chemical s......
The prefrontal cortex (PFC) and the striatum have mutual connections through direct and indirect pathways. Despite their......
Altered regional homogeneity of prefrontal cortex in Parkinson’s disease with mild cognitive impairm
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Humans demonstrate an inherent bias towards making maladaptive decisions,as shown by a phenomenon known as the gambl......
Impairment of postnatal dopaminergic maturation and adult behavior in disc1 knockdown mice by in ute
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Olanzapine Induces Inflammation and Immune Response via Activating ER Stress in the Rat Prefrontal C
Objective Antipsychotics,in particular olanzapine,are first-line medications for schizophrenia.The prefrontal cortex(PFC......
目的 探讨右前额叶在区分自我和他人面孔是否是必要的,从而更加全面地理解自我意识的神经基础.方法 采用1Hz重复经颅磁刺激(TMS)施......
目的探讨脑卒中后抑郁(PSD)大鼠额前皮质脑源性神经营养因子(BDNF)和其高亲和力受体酪氨酸激酶B(TrkB)蛋白的表达变化。方法利用线......
目的探讨脑卒中后抑郁(PSD)大鼠额前皮质脑源性神经营养因子(BDNF)mRNA和其高亲和力受体酪氨酸激酶受体B(TrkB)mRNA的表达变化。方......
目的探讨神经营养因子3(neurotrophic factor-3，NT-3)及其受体酪氨酸激酶受体C(tyrosine kinase receptors，TrkC)mRNA及蛋白在脑卒中......
目的探讨酒精依赖与miRNAs表达之间的关系，以及miRNAs在酒精依赖病理过程中可能的的作用机制。方法用灌胃法制备酒精依赖大鼠模型，将......
目的观察母婴分离(maternal separation，MS)对青年期小鼠海马和前额叶皮质糖皮质激素受体(glucocorticoid receptor，GR)和微管相关蛋......
目的探讨孕期束缚应激诱导的产后抑郁(postpartum depression，PPD)模型大鼠前额叶皮层催产素(oxytocin，OXT)及催产素受体(oxytocin r......
An abnormal resting-state functional brain network indicates progression towards Alzheimer’s disease
Brain structure and cognitive function change in the temporal lobe, hippocampus, and prefrontal cortex of patients with ......
Short-term environmental enrichment exposure induces proliferation and maturation of doublecortin-po
Previous studies have demonstrated that doublecortin-positive immature neurons exist predominantly in the superficial la......
目的 观察成年期甲状腺功能减退症(甲减)大鼠额叶突触结合蛋白I(synaptotagmin I,sytI)表达改变及不同剂量甲状腺素替代治疗的作用......
Brain regional changes of guanine nucleotide binding protein-inhabitant 2 in acute and chronic morph
BACKGROUND:Drug addiction involves two main central nervous systems,namely the dopamine and noradrenaline systems.These ......
